Mapelli graduated in Biomedical Engineering at Politecnico of Milan (2011) and obtained a translational PhD in computational science and oncology at the Institute of Oncology Research (Switzerland, 2019). Since 2012 sha is working in the field of computational oncology, focusing on genetic, epigenetic and transcriptional mechanisms of cancer deregulation. She joined the Experimental Immunopathology Group in 2020 to study the role of immune infiltrate in large cohorts of cancer patients, by integrating “omics” data.