Luca Beltrame graduated in Biotechnology and gained a PhD in Molecular Medicine at the University of Milan. He subsequently carried out his post-doc at the University of Florence. He coordinated the activities of the team of Bioinformatics of the Department of Oncology at the Istituto di Ricerche Farmacologiche Mario Negri IRCCS. He was an adjunct professor at the University of Pavia teaching Bioinformatics and he collaborated with Politecnico di Milano as a supervisor of PhD students in Biomedical Engineering.

In Humanitas, he is currently engaged in bioinformatic analyses at the Cancer Pharmacology Lab, regarding ovarian cancer. His other interests are on development of bioinformatic tools for reproducible data analysis.