Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression.
Piscuoglio S
J Pathol. 2016 Jan 25;238(4):508-18. doi: 10.1002/path.4672
The Genomic Landscape of Male Breast Cancers.
Piscuoglio S
Clin Cancer Res. 2016 Mar 9;22(16):4045-56. doi: 10.1158/1078-0432.CCR-15-2840
Alterations in homologous recombination repair genes in prostate cancer brain metastases.
Rodriguez-Calero A
Nat Commun. 2022 May 3;13(1):2400. doi: 10.1038/s41467-022-30003-5
DNA Methylation Landscapes of Prostate Cancer Brain Metastasis Are Shaped by Early Driver Genetic Alterations.
Gallon J
Cancer Res. 83(8):1203-1213. doi: 10.1158/0008-5472.CAN-22-2236
Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis.
Taha-Mehlitz S
Theranostics. 2021 Feb 15;11(9):4011-4029. doi: 10.7150/thno.50051
Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity.
Cyrta J
Nat Commun. 2020 Nov 3;11(1):5549. doi: 10.1038/s41467-020-19328-1
Standardizing Patient-Derived Organoid Generation Workflow to Avoid Microbial Contamination From Colorectal Cancer Tissues.
Marinucci M
Front Oncol. 2022 Jan 10;11:781833. doi: 10.3389/fonc.2021.781833
Discovery of synthetic lethal interactions from large-scale pan-cancer perturbation screens.
Srivatsa S
Nat Commun. 2022 Dec 14;13(1):7748. doi: 10.1038/s41467-022-35378-z
Analysis of off-tumour toxicities of T-cell-engaging bispecific antibodies via donor-matched intestinal organoids and tumouroids.
Harter MF
Nat Biomed Eng. 2023 Dec 19;8(4):345-360. doi: 10.1038/s41551-023-01156-5
Genetic profiling using plasma-derived cell-free DNA in therapy-naïve hepatocellular carcinoma patients: a pilot study.
Ng CKY
Ann Oncol. 29(5):1286-1291. doi: 10.1093/annonc/mdy083