Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.
Fossati G
Cell Death Differ. 2015 Feb 13;22(9):1425-36. doi: 10.1038/cdd.2014.227
Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects.
Tomasoni R
Elife. 2017 Mar 28;6pii: e21735. doi: 10.7554/eLife.21735
The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity.
Filipello F
Immunity. 2018 May 8;48(5):979-991.e8. doi: 10.1016/j.immuni.2018.04.016
Environmental regulation of the chloride transporter KCC2: switching inflammation off to switch the GABA on?
Pozzi D
Transl Psychiatry. 2020 Oct 15;10(1):349. doi: 10.1038/s41398-020-01027-6
Mutant prion proteins increase calcium permeability of AMPA receptors, exacerbating excitotoxicity.
Ghirardini E
PLoS Pathog. 2020 Jul 16;16(7):e1008654. doi: 10.1371/journal.ppat.1008654
The DNA repair protein ATM as a target in autism spectrum disorder.
Pizzamiglio L
JCI Insight. 2021 Feb 8;6(3)pii: 133654. doi: 10.1172/jci.insight.133654
Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia.
Scott-Hewitt N
EMBO J. 2020 Jul 13;39(16):e105380. doi: 10.15252/embj.2020105380
Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring.
Mirabella F
Immunity. 54(11):2611-2631.e8. doi: 10.1016/j.immuni.2021.10.006
Maternal immune activation leads to defective brain-blood vessels and intracerebral hemorrhages in male offspring.
Rasile M
EMBO J. 2022 Oct 31;41(23):e111192. doi: 10.15252/embj.2022111192
Microglia states and nomenclature: A field at its crossroads.
Paolicelli RC
Neuron. 110(21):3458-3483. doi: 10.1016/j.neuron.2022.10.020