Thermo Scientific™ UltiMate™ 3000 RSLCnano system is low-flow liquid chromatography system with improved nano-flow rate control resulting in high retention time precision and gradient reproducibility. The UltiMate 3000 RSLCnano suitable for virtually any low-flow LC or LCMS application such as bottom-up and top-down metabolomics when the available biological sample is extremely limited or for increase annotation coverage.